Design of New Antifungal Dithiocarbamic Esters Having Bio-Based Acrylate Moiety
ACS OMEGA(2019)
Abstract
Nine new dithiocarbamic esters derived from bio-based acrylic acid were synthesized and evaluated for their in vitro antifungal activity against the phytopathogenic fungus Fusarium solani and fungi-like oomycete Phytophthora infestans. Among these nine dithiocarbamic derivatives, compound 6 (tert-butyl 3-(N,N-diethyldithiocarbamoyl)-propanoate) showed interesting antifungal efficacy at low concentration compared to the other tested dithiocarbamates. The structure-antifungal activity relationship of these designed dithiocarbamic esters is discussed.
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Key words
new antifungal dithiocarbamic esters,acrylate moiety,bio-based
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