Neuropathy in sporadic inclusion body myositis: A multi-modality neurophysiological study

James H. Lee,Robert Boland-Freitas,Christina Liang,James Howells,Karl Ng

Clinical Neurophysiology（2020）

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摘要

•A majority of sIBM patients have conventional nerve conduction or thermal threshold abnormalities.•Markers of neuropathy in sIBM do not correlate with clinical markers of sIBM severity.•sIBM axons have altered excitability - depolarization or adaptation to myopathy are possible causes.

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关键词

Inclusion body myositis,Neuropathy,Nerve excitability,HCN channels,Ih

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