Targeting polyamine as a novel therapy in xenograft models of malignant pleural mesothelioma

Sze-Kwan Lam,Sheng Yan,Shi Xu,James Chung-Man Ho

Lung Cancer（2020）

引用 5|浏览12

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摘要

•Anticancer effects of DFMO in MPM xenografts.•Spermidine depletion, peroxynitrite elevation, inhibition of actin polymerization.•Activation of apoptosis.•Outstanding extended adjuvant treatment effect in the epithelioid mesothelioma model.

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关键词

MPM,ODC,DFMO,KC,CC3

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