One after another retinal involvement in lupus.

A 30-year-old woman was admitted to our hospital because of fever, arthralgia, butterfly erythema, al-opecia, and acute deterioration of the right visual acuity, which was 20/1,000 on ophthalmologic examination. She had no history of hypertension or diabetes mellitus. Laboratory findings on admission showed thrombocytopenia (9.9´104/µL) and lymphopenia (580/µL), but abnormal urinalysis and renal dysfunction were not observed. She possessed several autoantibodies, including antinuclear antibody (1:320 with speckled pattern) and anti-Sm antibody (100 U/mL). She was diagnosed with systemic lupus erythematosus (SLE) as she fulfilled the Systemic Lupus International Collaborating Clinics classification criteria (1). Furthermore, funduscopic examination revealed cotton-wool spots, narrowed branch retinal arteries, and retinal hemorrhage in her right eye (Figure 1). These findings were indicative of lupus retinopathy.