Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties
Ganesha Rai,Daniel J. Urban,Bryan T. Mott,Xin Hu,Shyh-Ming Yang,Gloria A. Benavides,Michelle S. Johnson,Giuseppe L. Squadrito,Kyle R. Brimacombe,Tobie D. Lee,Dorian M. Cheff,Hu Zhu,Mark J. Henderson,Katherine Pohida,Gary A. Sulikowski,David M. Dranow,Md Kabir,Pranav Shah,Elias Padilha,Dingyin Tao,Yuhong Fang,Plamen P. Christov,Kwangho Kim,Somnath Jana,Pavan Muttil,Tamara Anderson,Nitesh K. Kunda,Helen J. Hathaway,Donna F. Kusewitt,Nobu Oshima,Murali Cherukuri,Douglas R. Davies,Jeffrey P. Norenberg,Larry A. Sklar,William J. Moore,Chi Dang,Gordon M. Stott,Leonard Neckers,Andrew J. Flint,Victor M. Darley-Usmar,Anton Simeonov,Alex G. Waterson,Ajit Jadhav,Matthew D. Hall,David J. Maloney Journal of Medicinal Chemistry(2020)
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