Protein profile of ear auricle cartilage and the important role of ITGB1/PTK2 in microtia.

Weiwei Dong,Haiyue Jiang,Leren He,Bo Pan,Lin Lin,Yupeng Song,Qinghua Yang

International Journal of Pediatric Otorhinolaryngology（2020）

引用 4|浏览11

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摘要

The research locates the key protein Integrin Beta-1, and verified it at the mRNA level. The increasing level of ITGB1 and decreasing of PTK2 may play an important role in congenital ear deformity. This research will inspire more otolaryngologists and orthopedics doctors to pay attention to the etiology and mechanism of microtia.

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关键词

Microtia,DIA,Phosphorylation,ITGB1/PTK2,Auricle cartilage

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