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Genetic and Epigenetic Landscape of the Molecular Immuno-Signature in HNSCC

J Hess, B Feng, Y Shen, Q Huang, X Pastor Hostench, M Bieg, M Plath, P Huber, N Ishaque, R Eils, K Freier, W Weichert, K Zaoui

Laryngo-, Rhino-, Otologie(2020)

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Abstract
Malignant progression exhibits a tightly orchestrated balance between immune effector response and tolerance. However, underlying molecular principles that drive the establishment and maintenance of hot and cold tumor phenotypes remain to be elucidated.
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