Effects of age and social isolation on murine hippocampal biochemistry and behavior

Annabelle Panossian, Michael W Cave,Bhavik A Patel,Emily L Brooks,Melanie S Flint,Mark S Yeoman

Mechanisms of Ageing and Development（2020）

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摘要

•Social isolation (SI) alters behavior and brain biochemistry in young mice.•Old mice either failed to respond or showed a synergistic response with age to SI.•Both responses could contribute to the health risks of SI.

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关键词

Social isolation,Stress,Aging,Serotonin,Inflammation,Memory,Hippocampus

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