Spraying rhubarb powder solution under gastroscope in the treatment of acute non varicose upper gastrointestinal bleeding: A systematic review and meta analysis of randomized controlled trials

•Significantly improved effect.•Shorten the time of immediate hemostasis.•Reduce rebleeding events.•Therapeutic drugs with better efficacy and fewer side effects may be found.•To treat acute non-varicose upper gastrointestinal bleeding and summarize new treatment methods.