Comparative genome-wide DNA methylation analysis in myocardial tissue from donors with and without Down syndrome

Romina B Cejas,Jie Wang,Rachael Hageman-Blair,Song Liu,Javier G Blanco

Gene（2021）

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摘要

•Global DNA methylation is similar in DS and non-DS myocardium.•There is a small number of differentially methylated loci in DS myocardium.•58% of genes overlapping with DMR codify for proteins with known functions.

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关键词

DS,non-DS,DNA,RUNX1,RNA,mRNA,DMR,SNP,FDR,ACTB,PCR,RT-qPCR,DSCR,GO,RRBS

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