Multifunctional properties of acetaminophen immobilized polymer nanohybrid composites

The present work describes the acid functionalization of single-walled carbon nanotubes (SWCNTs) with N -acetyl- p -amino phenol methacrylate (APM) of structural, thermal, morphological electrochemical and biological properties. The target nanohybrid composites were obtained by the condensation reaction between SWCNT, N -acetyl- p -amino phenol and methacrylic anhydride. The N -acetyl- p -aminophenol methacrylate [APM] was successfully immobilized with SWCNTs by free radical polymerization technique (FRP). The uniform dispersion on SWCNTs was achieved by functionalization of APM on the SWCNT surface, and the stability confirms up to 8 months. The stability enhancement is due to strong interaction of the SWCNTs carboxylic group with the amide moieties of the polymer. The morphological studies were performed by FE-SEM and HR-TEM, which shows distinct morphological architecture based on the arrangement of nanotubes into the polymer. The synthesized nanocomposites were characterized through various spectroscopic measurements. The anti-cancer studies, results obtained by this process are ideal, and showed optimal percentage of cancer cell death upon a 48 h cell line analysis. Graphic abstract