Non-Hydrogen Bond Catalyst-Mediated Diastereoselective Conjugate Additions Of 5h-Oxazol-4-Ones Too-Hydroxyphenyl-Substitutedp-Quinone Methides
ORGANIC & BIOMOLECULAR CHEMISTRY(2020)
摘要
An efficient DBU-catalyzed conjugate addition of 5H-oxazol-4-ones too-hydroxyphenyl-substitutedp-quinone methides has been developed, affording the valuable diarylmethanes in high yields with excellent diastereoselectivity. This strategy demonstrates a robust access to a wide range of diarylmethane derivatives possessing biologically significanto-hydroxyphenol andp-hydroxyphenol moieties under mild reaction conditions.
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