Transient Pancytopenia Subsequently Diagnosed With Acute Leukemia: A Report Of 4 Cases Of Acute Lymphoblastic Leukemia And Acute Myeloid Leukemia
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY(2021)
Abstract
A transient pancytopenic phase has been described in pediatric leukemia. The characteristic complete recovery of peripheral counts can obscure a clinician's suspicion for malignancy and may impact subsequent follow-up care. The authors describe 4 pediatric patients that had transient pancytopenia with an initial abnormal marrow finding. These patients were subsequently diagnosed with acute leukemia within 5 months of presentation. Awareness of this phenomenon by the provider and education of families may help with the appropriate and timely diagnosis of subsequent leukemia.
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Key words
Preleukemia, leukemia, transient pancytopenia
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