Understanding performance of 3D-printed sorbent in study of metabolic stability

Szymon Ulenberg,Paweł Georgiev,Mariusz Belka,Grzegorz Ślifirski,Martyna Wróbel,Andrzej Chodkowski,Marek Król,Franciszek Herold,Tomasz Bączek

Journal of Chromatography A（2020）

引用 7|浏览19

暂无评分

摘要

•The 3D-printed sorbent is coupled to the metabolic stability test of drug candidates.•Customizable sorbent enhances the performance of LC-MS analysis at low cost of sample clean-up.•The additional extraction step improves the precision of drug candidates’ t1/2 determination.

查看译文

关键词

3D-printed sorbent,Metabolic stability,Advances in pharmaceutical analysis,Microsomes,Solid-phase microextraction (SPME)

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要