Histomorphometric Measure Of Disorder Of Collagen Fiber Orientation Is Associated With Risk Of Recurrence In Er Plus Breast Cancers In Ecog-Acrin E2197 And Tcga-Brca

Background: Recent research has shown that collagen fiber arrangement in the tumor microenvironment plays a key role determining breast cancer prognosis. In this work, we present a new quantitative histomorphometric approach to identify and evaluate whether Collagen Fiber Orientation Disorder from Tumor-associated Stroma (CFOD-TS) on digitized HE 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-06-16.