A class I histone deacetylase is implicated in the encystation of Entamoeba invadens

International Journal for Parasitology(2020)

Cited 5|Views19
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Abstract
•Levels of histone H4 acetylation are regulated in a stage‐specific manner.•Histone hyperacetylation negatively affects the encystation of Entamoeba invadens.•Several metabolic pathways are downregulated by Trichostatin A treatment during encystment.•A class I histone deacetylase could be implicate in the encystation of Entamoeba invadens.
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Key words
Entamoeba invadens,Encystation,Histone acetylation,Histone deacetylases,Trichostatin A,Histone posttranslational modifications
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