Pharmacokinetic and safety study of co-administration of albendazole, diethylcarbamazine, Ivermectin and azithromycin for the integrated treatment of Neglected Tropical Diseases.

Lucy N John,Catherine Bjerum,Pere Millat Martinez,Rhoda Likia,Linda Silus, Chilaka Wali,Arthur Elizah,Yashpal S Chhonker,Veenu Bala,Christopher L King,Daryl J Murry,Oriol Mitja,Michael Marks

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2020）

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摘要

Co-administration of AZI with IDA did not show evidence of significant drug-interactions. There were no serious AEs in any of the study arms. Our data support further evaluation of the safety of integrated MDA for NTDs.Clinical Trials Registration. NCT03664063.

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关键词

co-administration,lymphatic filariasis,mass drug administration,yaws

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