The draft genome sequence of Meyerozyma guilliermondii strain YLG18, a yeast capable of producing and tolerating high concentration of 2-phenylethanol

The draft genome of a wild-type Meyerozyma guilliermondii strain YLG18, which could convert l -phenylalanine ( l -phe) to 2-phenylethanol (2-PE) and tolerate high concentration of 2-PE was sequenced and analyzed. 18S rDNA analysis indicated that strain YLG18 is closely related to M. guilliermondii . The assembled draft genome of strain YLG18 is 12.8 Mb, containing 5275 encoded protein sequences with G + C content of 43.75%. Among these annotated genes, two aminotransferases, one phenylpyruvate decarboxylase and two bifunctional alcohol dehydrogenases ( adh ) play key roles in the achievement of 2-PE production from l -phe via Ehrlich pathway. In addition, membrane protein insertase ( YidC ), heat shock protein ( Hsp90 ) and chaperons ( SGT1 ) were identified, which may contribute to the increased tolerance to 2-PE.