Relationships between increased circulating YKL-40, IL-6 and TNF-α levels and phenotypes and disease activity of primary Sjögren's syndrome

Caiqun Chen,Yan Liang,Zhiyu Zhang,Zhencheng Zhang,Zaixing Yang

International Immunopharmacology（2020）

Cited 12|Views11

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Abstract

•Serum levels of YKL-40, IL-6 and TNF-α were increased in pSS patients.•YKL-40, IL-6 and TNF-α were mainly involved in systemic inflammation of pSS.•Each of YKL-40, IL-6 and TNF-α had separate association with distinct pSS phenotype.

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Key words

YKL-40,Primary Sjögren's syndrome,Interleukin-6,Tumor necrosis factor α

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