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鼻呼出一氧化氮在富氢盐水灌洗鼻腔治疗变应性鼻炎中的变化及意义

Ling JIN,Kai FAN,Xi ZHANG,Yihua ZHAO,Qin GE,Yang WANG,Shaoqing YU

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery（2020）

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Abstract
目的:观察富氢盐水对鼻呼出一氧化氮(nNO)浓度的影响,探讨其治疗变应性鼻炎的可能机制.方法:临床筛选20例持续性中重度变应性鼻炎患者,先后用富氢生理盐水及生理盐水灌洗鼻腔,进行随机双盲自身对照研究,每周测试nNO值.结果:nNO值与变应性鼻炎的诊断及疗效有相关性,2种灌洗液治疗前后nNO值的差异有统计学意义(P＜0.01).结论:富氢盐水灌洗鼻腔可以引起nNO的改变,有望用于变应性鼻炎的治疗.
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Key words
lavage nasal,nasal nitric oxide,normal saline,rhinitis, allergic
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