Stimulus-Responsive Sequential Release Systems for Drug and Gene Delivery.

Sepideh Ahmadi,Navid Rabiee,Mojtaba Bagherzadeh, Faranak Elmi,Yousef Fatahi,Fatemeh Farjadian,Nafiseh Baheiraei,Behzad Nasseri,Mohammad Rabiee,Niloufar Tavakoli Dastjerd,Ali Valibeik,Mahdi Karimi,Michael R Hamblin

Nano Today（2020）

引用 111|浏览2

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摘要

•An in-depth discussion on stimulus responsive sequential drug/gene release systems.•Mechanistic aspects of sequential cargo delivery systems are discussed.•Different stimulus factors determining sequential release are reviewed.•A discussion on recent technologies, advances and limitations is provided.

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关键词

Sequential drug and gene release,Stimulus-responsive nanoparticles,Cancer nanomedicine,Temporal control,Synergistic combinations

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