Individual patient data meta analysis of EVAR trial 1, the Dutch Randomised Endovascular Aneurysm Management trial, the Open versus Endovascular Repair trial and Anévrysme de l …

The UK EndoVascular Aneurysm Repair (EVAR) randomised controlled trials: long-term follow-up and cost-effectiveness analysis(2018)

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MethodsIn July 2013, MEDLINE, EMBASE and clinical trial databases were searched for randomised trials comparing OR and EVAR of AAAs. The search terms used were AAA, aneurysm, endovascular, stent, open repair and randomised trial. From 275 reports, we identified four eligible trials reporting mid-term follow-up. The methods for these four multicentre trials included in this meta-analysis have been published previously. 94, 102, 105, 106 EVAR-1 randomised 1252 patients (91% male), with an aneurysm diameter of> 5.5 cm, between September 1999 and August 2004 in the UK. The DREAM trial randomised 351 patients (92% male), with an aneurysm diameter of≥ 5 cm, between November 2000 and December 2003 in the Netherlands and Belgium. The OVER trial randomised 881 patients (99% male), with an aneurysm diameter of≥ 5.0 cm, between October 2002 and April 2008 at Veteran Affairs …
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