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Anti-Stress Effects Of Rosemary (Rosmarinus Officinalisl.) Leaf Extract On Intestinal Goblet Cells And Immobility Of Forced-Swimming Test In Balb/C Mice

Tomoko Kayashima,Koji Nagao, Mituki Umino, Hiroko Kaikiri,Sachi Shibata,Kiminori Matsubara

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY（2020）

Cited 1|Views9
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Abstract
We investigated the anti-stress effect of rosemary (Rosmarinus officinalisL.) leaf extract (RLE) on restraint-stressed mice and found that RLE alleviated decreases in the number of intestinal goblet cells and amount of hepatic triglycerides. It also decreased the immobility time in the forced-swimming test and activation of microglia in the brain, suggesting that RLE has beneficial effects on stress-induced dysfunctions.
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Key words
Rosemary, goblet cells, stress, hepatic triglyceride, forced-swimming test
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