Changes in expression of Kv7.5 and Kv7.2 channels in dorsal root ganglion neurons in the streptozotocin rat model of painful diabetic neuropathy

Neuroscience Letters(2020)

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摘要
•Expression of Kv7.5 and Kv7.2 was examined in DRG neurons in normal and STZ rats.•Kv7.5 expression is downregulated in small/medium DRG neurons in STZ rats.•Kv7.2 expression is upregulated in small DRG neurons in STZ rats.•The findings implicate Kv7 channels in mechanisms of diabetic neuropathy.
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关键词
Diabetic neuropathy,Primary sensory neurons,K+ channels
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