Water-soluble amphiphilic ruthenium(ii) polypyridyl complexes as potential light-activated therapeutic agents.
CHEMICAL COMMUNICATIONS(2020)
Abstract
Two water-soluble amphiphilic Ru(ii) polypyridyl complexes containingN-1,10-phenanthrolin-5-yldocosanamide and 1,10-phenanthroline (phen) or 1,4,5,8-tetraazaphenanthrene (TAP) as ligands were synthesised and their photophysical and photobiological properties evaluated; both complexes showed a rapid cellular uptake and displayed phototoxicity against HeLa cervical cancer cells.
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Key words
polypyridyl complexes,water-soluble,light-activated
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