Constrictive Infectious Pericarditis Caused by Propionibacterium acnes

semanticscholar(2020)

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摘要
action). Furthermore, South Asians in our series presented a significantly lower prevalence of hypertension, smoking, and cocaine abuse than the white Spanish population, with similar values of low-density lipoprotein cholesterol, but a lower prevalence of previous treatments with statins. Studies performed in Britain have reported contradictory results regarding the presence of these risk factors in South Asian patients, and this has been related to the heterogeneity of the subgroups analyzed, which makes extrapolation to our setting difficult. For its part, the risk profile observed among the young Spaniards in our series is in keeping with previous findings, in which early infarction has been associated with high rates of smoking and hypercholesterolemia, and glucose metabolism disorders have a smaller role. Our study highlights the specific features of cardiovascular risk in South Asians in our setting and the differences with respect to the young Spanish population. There were no significant differences between the 2 groups in the clinical presentation of AMI (with or without ST elevation). Nonetheless, among patients with ST elevation AMI, there was a significantly higher percentage of anterior AMI in South Asian patients. In addition, coronary angiography showed more severe disease in these patients, and a larger number were considered to have nonrevascularizable lesions. AMI without coronary lesions was more common in the white Spanish population. These observations indicate that coronary disease in South Asians is related more to accelerated atherosclerosis than to predominantly thrombotic or vasospastic processes. Despite the differences described, the 2 groups presented a similar in-hospital clinical course with low complication rates and mortality, which was likely due to the young age of the patients, low prevalence of comorbidities, absence of significant differences in the treatment received, and the improved in-hospital prognosis of AMI observed in our setting. This series is the first in Spain to address ischemic heart disease in South Asian immigrant patients. Knowledge of the differential characteristics of this ethnic group can facilitate the development of primary and secondary prevention strategies adapted to their risk profile.
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