Current Trends in Efficient Production of 1 , 3-Propanediol

1,3‐Propanediol, a highly needed multifunctional molecule, can be produced from different resources using microorganisms. According to its useful properties during the synthetic reactions, 1,3‐Propanediol is a promising targeted product exceptionally in chemical industries such as polymer and cosmetic industries. By considering 1,3‐PD as a natural product, it therefore be produced throughout fermentation processes by optimizing some related biochemical pathways. In this article, we reviewed and presented different strategies for the microbial production of 1, 3‐propanediol with their advantages and disadvantages. Furthermore, metabolic and genetic engineering could significantly enhance product yields and therefore, overcome the challenges of fermentation engineering. This review describes the production of 1,3‐propanediol by wild and engineered strains. It also tries to discuss about the different ways concerned in the use of crude glycerol for 1,3‐PD production, with particular emphasis laid on biodiesel industries. Present review also summarizes the current state of technics applied for the downstream processing and purification of 1,3‐propanediol produced biologically. The future prospect of 1,3‐propanediol and its efficiency as a main bulk compound are also reviewed under the light of the present study.