SETD 7 controls intestinal regeneration and tumorigenesis by 1 regulating Wnt / β-Catenin and Hippo / YAP signaling 2 3

The Biomedical Research Centre and Department of Microbiology and Immunology,, 9 University of British Columbia, Vancouver, BC, V6T1Z3, Canada; The Structural 10 Genomics Consortium, Princess Margaret Cancer Centre and Department of Medical 11 Biophysics, University of Toronto, Toronto, ON, M5G1L7, Canada; Department of 12 Gastroenterology, School of Medicine, Keio University, Tokyo, 160-8582, Japan; 13 Department of Medical Genetics, University of British Columbia, Vancouver, BC, 14 V6T1Z3, Canada; Worldwide Medicinal Chemistry, Pfizer Worldwide Research and 15 Development, Cambridge, MA 02139, USA; Department of Pathology and Laboratory 16 Medicine, University of British Columbia, Vancouver, BC, V6T1Z3, Canada; Infection 17 and Immunity Program, Monash Biomedicine Discovery Institute and Department of 18 Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, 3800, 19 Australia. 20