"suboptimal" kidney donors

Female, pecliatric, and older donors have bee~'~ elated with iDfer10r paft IlU'Vivai after reDaI. traD8plantation. We anaIyzecl these three sublP'Oups°in 88'7 patients receivina tacrolhnua-bued. immunosuppression. There were no cWrerences in recipient age, incidence of retransplantation, or percentage of 8eD8ltized patients. Female donors, compared with male donors, were 8880Clated with comparable 1and a-year patient 81U"Vlval rates (98% and 93% VB. 95% and 91%, respectively) and comparable 1and a-year graft survival rates (90% and 80% va. 88% and 81 %, respectively). Renal function was also slmilar. Recipients of pediatric en bloc kidneys, when compared with recipients of other cadaveric kidneys, also had comparable 1and a-year patient survival rates (94% and 94% VB. 95% and 91%, respectively) and comparable 1and a-year graft survival rates (84% and 84% VB. 89% and 79%, respectively). Renal function was better in recipients of en bloc kidneys, with a mean serum creatinine level of 1.4%1.8 mgldl vs. 2.0%1.5 mg/dl (P=O.OI). In contrast to the first two subgroups, donors over 80 yean of age, when compared with donors under 80 yean of age, were associated with worse 1and a-year patient survival rates (88% and 80% vs. 98% and 94%, respectively; P更多