Major rearrangements in the 70 S ribosomal 3 D structure caused by a conformational switch in 16 S ribosomal RNA

1The Wadsworth Center, 4Howard Hughes Medical Institute, Health Research, Inc. at Wadsworth Center and 3Department of Biomedical Sciences, State University of New York at Albany, Empire State Plaza, Albany, NY 12201-0509, 5Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111-1800 and 6Department of Molecular and Cell Biology and Biochemistry, Division of Biology and Medicine, Brown University, Providence, RI 02912, USA