Title : Elevated basal serum typtase identifies a multisystem disorder associated with increased α 1

5 Authors: Jonathan J. Lyons, MD, Xiaomin Yu, Ph.D, Jason D. Hughes, PhD, Quang T. Le, 6 PhD, Ali Jamil BS, Yun Bai, MS, Nancy Ho, MD, Ming Zhao, PhD, Yihui Liu, PhD, 7 Michael P. O’Connell, PhD, Neil N. Trivedi, MD, Celeste Nelson, CRNP, Thomas DiMaggio, 8 ADN, Nina Jones, RN, BSN, Helen Matthews RN, BSN, Katie L. Lewis, ScM, Andrew J. 9 Oler, PhD, Ryan J. Carlson, BS, Peter D. Arkwright, FRCPCH, D Phil, Celine Hong, PhD, 10 Sherene Agama, BS, Todd M. Wilson, DO, Sofie Tucker, BA, Yu Zhang, PhD, Joshua J. 11 McElwee, PhD, Maryland Pao, MD, Sarah C. Glover, DO, Marc E. Rothenberg, MD, PhD, 12 Robert J. Hohman, PhD, Kelly D. Stone, MD, PhD, George H. Caughey, MD, Theo Heller, 13 MD, Dean D. Metcalfe, MD, Leslie G. Biesecker, MD, Lawrence B. Schwartz, MD, PhD, 14 and Joshua D. Milner, MD. 15