Analysis of Two Major Intracellular Phospholipase A 2 s in Mast Cells Reveals Crucial Contribution of cPLA 2 α , not iPLA 2 β , to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts

From the Lipid Metabolism Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 256-8506, Japan; Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan; Department of Biochemistry and Molecular Biology, Department of Lipidomics, and Department of Metabolome, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; The Laboratory of Molecular Genetics, Department of Medical Genetics, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan; and Core Research for Evolutional Science and Technology (CREST) and Precursory Research for Embryonic Science and Technology (PRESTO) of the Japan Science and Technology Agency,, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata, 997-0052, Japan; College of Life and Health Sciences, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan.