Visual Analysis of Abnormal Thickness of Intraretinal Layers

Optical coherence tomography (OCT) enables high-resolution 3D imaging of intraretinal layers to understand a variety of retinal and systemic disorders. Yet, discovering and relating localized changes of layers in complex OCT datasets is challenging. We propose a combination of systematic data reduction and interactive visualization to support the analysis of abnormal layer thickness. First, we classify and extract regions of abnormal thickness per retinal layer. Second, we compile the regions in a composite map and show their spatial distribution in a novel overview visualization. Third, we integrate coordinated interaction to quickly browse through the data and investigate selected regions in detail. Altogether, our solution enables a fast and targeted analysis of abnormal changes of intraretinal layers for assisting medical diagnoses.