ACGS Best Practice Guidelines for Variant Classification 2019

1. Department of Molecular Genetics, Royal Devon & Exeter NHS Foundation Trust, Exeter, EX2 5DW, UK. 2. University of Exeter Medical School, Exeter, EX2 5DW, UK. 3. Department of Clinical Genetics, Royal Devon & Exeter NHS Foundation Trust, Exeter, EX2 5DW, UK. 4. Genomics England, William Harvey Research Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK 5. Leeds Genetics Laboratory, St James’s University Hospital, Leeds LS9 7TF, UK. 6. Bristol Genetics Laboratory, North Bristol NHS Trust, Bristol BS10 5NB, UK. 7. Wessex Clinical Genetics Service, University Hospital Southampton, Southampton SO16 5YA, UK. 8. East Anglian Medical Genetics Service, Addenbrooke’s Hospital, Cambridge CB2 0QQ, UK. 9. Department of Clinical Genetics, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK. 10. UK NEQAS for Molecular Genetics, Department of Laboratory Medicine, Royal infirmary of Edinburgh, Edinburgh EH16 4SA, UK. 11. Oxford Genetic Laboratories, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LE, UK. 12. Viapath Genetics Laboratory, Viapath Analytics LLP, 5 th Floor Tower Wing, Guy’s Hospital, London SE1 9RT, UK. 13. Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK. 14. Evolution and Genomic Science, University of Manchester, Manchester M13 9PL 15. West Midlands Regional Genetics Laboratory, Birmingham Women’s NHS Foundation Trust, Birmingham, B15 2TG, UK.