Bioengineering the Lung : Molecules , Materials , Matrix , Morphology , and Mechanics Moraxella catarrhalis induces an immune response in the murine lung that is independent of human CEACAM 5 expression and long-term smoke exposure

Birgitt Gutbier,* Katja Fischer,* Jan-Moritz Doehn, Carolin von Lachner, Christian Herr, Esther Klaile, Ursula Frischmann, Bernhard B. Singer, Kristian Riesbeck, Wolfgang Zimmermann, Norbert Suttorp, Sebastian Bachmann, Robert Bals, Martin Witzenrath, and Hortense Slevogt Department of Infectious Diseases and Pulmonary Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany; Septomics Research Center, Jena University Hospital, Jena, Germany; Department of Internal Medicine V–Pulmonology, Allergology, Respiratory Intensive Care Medicine, University of the Saarland, Homburg Saar, Germany; Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany; Institute of Anatomy, Medical Faculty, University Duisburg-Essen, Essen, Germany; Clinical Microbiology, Department of Translational Medicine Malmö, Lund University, Malmö, Sweden; Tumor Immunology Laboratory, LIFE-Center, Klinikum Grosshadern, Ludwig-Maximilians-University Munich, Munich, Germany; and Department of Anatomy, Charité-Universitätsmedizin Berlin, Berlin, Germany