Development of Donor Recipient Chimeric Cells of bone marrow origin as a novel approach for tolerance induction in transplantation.
Stem cell investigation（2021）
摘要
This study confirmed feasibility of DRCC creation via PEG mediated fusion. The created DRCC revealed pro-tolerogenic properties indicating potential immunomodulatory effect of DRCC therapy when applied to support tolerance induction in solid organ and vascularized composite allograft transplantation.
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关键词
Donor recipient chimeric cell (DRCC),cell fusion,cell therapy,immunomodulation,transplantation
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