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Reproducibility of Renal Blood Volume Measurements in Mice

Chad Quarles, Feng Weng,Mohammed Tantawy,Rosie Jiang,Keiko Takahashi,Chuan-Ming Hao,Todd Peterson,Raymond Harris,Takamune Takahashi

semanticscholar（2011）

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Abstract
Introduction: Susceptibility based relative blood volume (RBV) mapping methods are widely used to assess normal and pathological differences in tissue vascular density. Renal RBV measurements could provide a valuable tool to characterize abnormal renal perfusion in mouse models of kidney disease. In this study, we optimized MRI acquisition methods for RBV mapping in mouse kidneys and assessed the reproducibility of RBV measurements acquired on consecutive days.
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