Vitamin d status & its relation with bone pain in adult bangladeshi women: a study at a jci accredited hospital in bangladesh

The present cross-sectional study was designed to evaluate the vitamin D status in adult Bangladeshi women by using serum 25 hydroxyvitamin D (S-25-OHD) and its relation with bone pain; a study in a JCI accredited hospital in Bangladesh. We consecutively studied 1013 women belonging to two groups. Apparently healthy women of reproductive age (15-45 years; group A, N = 486 mean ± SD age 33.3 ± 8.3 years) and postmenopausal women (46-70 years; group B, N = 527 mean ± SD age 57.7 ± 8.1 years) were the subjects of the study. The subjects in groups A, and B were randomly selected from the Apollo Hospitals Dhaka whose are came to the doctor in different illness. The mean value of S-25-OHD in group A was significantly different compared with groups B (50.4 ± 23.6 nmol/l vs. 39.6 ± 18.1 nmol/l, respectively; P =0.04). No subject showed a serum 25 OHD level above the normal range (75-250 nmol/l) and the distribution in two groups was very close to the lower limit of the deficient range (<25nmol/l). Vitamin D deficiency (S-25-OHD level <25 nmol/l) was Observed in 11.0% in group A & 20.0 % in group B, respectively. The insufficiency (S-25-OHD level 25-74 nmol/l) of Vitamin D was surprisingly very high in two groups; the prevalence was 60.0 % in group A & 75.0 % in Group B, respectively. In case of sufficiency, there is a Remarkable change between two groups. The prevalence was 29.0% in group A & only 5.0 % in group B, respectively. In our present study, the bone pain was extremely high in group B (67%) than group A (35%). In conclusion, the results of this study suggest that deficiency and insufficiency of vitamin D status are common in adult Bangladeshi women that they were equally at risk of developing vitamin D deficiency. Hypovitaminosis D could be an important public health problem in adult women of Bangladesh. In case of bone pain, the postmenopausal women are sigficantly high risk than the reproductive women due to lack of serious vitamin D insufficiency.