Small Vessels – Big Problems : Novel Insights into Microvascular Mechanisms of Diseases Effect of PDE 5 inhibition on the modulation of sympathetic-adrenergic vasoconstriction in contracting skeletal muscle of young and older recreationally active humans

Michael Nyberg, Peter Piil, Jon Egelund, Randy S. Sprague, Stefan P. Mortensen, and Ylva Hellsten Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark; Department of Pharmacological and Physiological Science, St. Louis University School of Medicine, St. Louis, Missouri; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark; and The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark