t library enables rapid synthetic expansion yielding the fi rst reported inhibitors of PHIP ( 2 ) , an atypical bromodomain †

Structural Genomics Consortium (SGC), Un Target Discovery Institute (TDI), Nuffield Oxford, Oxford OX3 7FZ, UK. E-mail: paul.b Diamond Light Source (DLS), Harwell Scien 0DE, UK. E-mail: frank.von-del@diamond. Department of Chemistry, School of Life Sci 9QJ, UK Kennedy Institute of Rheumatology, N Rheumatology and Musculoskeletal Science Headington, Oxford OX3 7FY, UK Department of Biochemistry, University of J Africa † Electronic supplementary informa 10.1039/c5sc03115j Cite this: Chem. Sci., 2016, 7, 2322