PAF & Arachidonic Acid Cascade

Tadaomi Aikawa, Hong Yang, Toshio Shimada, Manalm Koyanagi, Itsuro Matsumoto, Katsuro Iwasaki, Shin-ichiro Ucbiyama, Yoshihisa Amakasu, Yoshitaka Miyazaki,Hiroshi Kuwata, Satoko Shimbara,Yoshihito Nakatani, Gen-ichi Atsumi,Makoto Murakami,Ichiro Kudo, Nobuo Takasu, Kazushige Tanaka, Takefumi Gemba

Inflammation Research(2014)

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摘要
The aim of the study was to examine the activity of neutrophils taken from synovial fluid of patients with rheumatoid arthritis. Sam pies were taken before and after cryotherapy. The activity of neutrophils prestimulated with opsonized zymozan was measured by chemiluminescence. It was shown that, in the majority of patients chemiluminescence was more intense before treatment but became less intense after cryotherapy. Conclusion: Results show that cryotherapy, irrespective ofthe level of chemiluminescence, norrnalizes the activity of neutrophils stimulated with opsonized zymozan. P-II-6-20
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