Study of oxidative stress and serum paraoxonase 1(pon 1) in essential

Aim and Objectives: of the most important risk factors for cardiovascular diseases and other clinical outcomes. Even though lot of research has been done for the treatment and prevention o out with the objective to find out correlation between oxidative stress and paraoxonase 1 in hypertension (HTN). Methods: diabetes mellitus, thyroid disease, chronic kidney disease, smoking, autoimmune diseases and any other chronic diseases are excluded. The study was approved by Institutiona was obtained from all cases. Serum PON 1 was estimated by ELISA method using commercial kit procured from Aviscera Bioscience, total oxidant load by FOX 2 assay and total antioxidant capacity by FRAP assay. Statistical Results: antioxidant enzyme (PON 1) was decreased in hype serum FOX2 with serum FRAP and PON1 level Conclusion: total antioxidant capacity. PON 1 is an antioxidant enzym decreased which is responsible for prevention of HTN and it’s complications.