Personalized Medicine and Imaging Serum Interleukin-8 Re fl ects Tumor Burden and Treatment Response across Malignancies of Multiple Tissue Origins

M. Sanmamed, Omar Carranza-Rua,C. Alfaro,O. Carmen, Nate,S. Martı́n-Algarra,G. Pérez, S. F. Landazuri,Álvaro González,S. Gross,I. Rodriguez, noz-Calleja,M. Rodriguez-Ruiz, B. Sangro,M. Rizzo,G. Mazzolini,J. I. Pascual,M. Andueza, J. Pérez-Gracia, I. Melero

semanticscholar（2014）

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摘要

Purpose: Interleukin-8 (IL8) is a chemokine produced by malignant cells of multiple cancer types. It exerts various functions in shaping protumoral vascularization and inflammation/immunity. We evaluated sequential levels of serum IL8 in preclinical tumor models and in patients to assess its ability to estimate

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