Methodology for the Identification of Pesticide Metabolites in Complex Matrices Using UPLC-ToF / MSE and the UNIFI Scientific Information System

semanticscholar(2015)

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摘要
■ ■ Streamlines registration of new pesticide products by facilitating metabolite identification in complex matrices. IN T RO DU C T IO N Regulatory agencies such as the U.S. EPA require extensive documented and audited studies concerning the benefits and possible risks of using crop protection products before registration can occur. For example, manufacturers must provide evidence of the potential human health and environmental effects. One such example includes the metabolic fate of the active ingredient(s) (AI) of a new product and the effects that potential metabolites can have on the overall environmental or human toxicity. Therefore, the accurate measurement of metabolites is important to assess the risk of exposure and to provide thorough product risk assessment.
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