ASSOCIATION OF VITAMIN D-3 WITH LUNG FUNCTION AND EXERCISE TOLERANCE IN STABLE COPD PATIENTS: A CROSS-SECTIONAL STUDY

COPD patients, which will be helpful for physicians to make a decision to give palliative care in terminal COPD patients. Methods: Many physiological and laboratory parameters were recorded in COPD patients, and all these patients were followed up at least for one year. Multivariable analysis for one year mortality was conducted, and we used the independent variables to construct a composite index, a multidimensional 11-point scale in which higher scores indicate a higher risk of death. Results: A total of 558 patients were finally included in the analysis. Thirty seven patients died within one year after enrolment. mMRC score and SaO2 level were independent variables for predictors of one year mortality. The 11-point scale of this DO index showed that one year mortality in groups with scale 0–3, 4-7, 8–11 were 96.9%, 83.1%, and 37.5% respectively, and two year mortality in groups with scale 0–3, 4–7, 8–11 were 92.3%, 66.7%, and 25% respectively. Validation of this DO index in another cohort is still ongoing. Conclusion: Composite DO index with 11-point scale may be a useful tool for predicting recent mortality, which will be helpful for physicians to make a decision for palliative care in terminal COPD patients