Isoindole-1 , 3-dione-based α ,-diketo acid bioisosteres as hepatitis C virus NS 5 B polymerase inhibitors

Ravindra Ramesh Deore, Ajit Dhananjay Jagtap, Pei-Teh Chang, WirunyaTrimethasil and Ji-Wang Chern School of Pharmacy and Center for Innovative Therapeutics Discovery, National Taiwan University, No. 1, Section 1, Ren-Ai Road, Taipei 10051, Taiwan, and Department of Life Science, College of Life Science, National Taiwan University, No. 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan, and Faculty of Pharmaceutical Science, Khon Kaen University, Khon Kaen, 40002, Thailand.