Other hearing loss Esophageal cancer Otitis media Mouth cancer Cancer of other part of pharynx and orophatynx Larynx cancer Nasopharynx cancer Upper respiratory infections Thyroid cancer

R esearch priority setting is essential for efficient and equitable use of limited health resources.1 This is a challenging process because of the large number of stakeholders involved, the numerous methods available for prioritization, and the lack of consensus on which method is appropriate.1 Some factors that contribute to decision making regarding research funding and efforts include interest group advocacy, disease transmissibility, political support, infrastructure building, and portfolio diversification.2,3 The appropriate allocation of available resources is in the best interest of all those involved with the health system. This system includes policy makers, health professionals, and patients, with research and service provision funds coming from the same pool of scarce health resources.1,4 There are various efforts under way to help drive agendas and priorities within the field of otolaryngology. For instance, ENT UK5 launched the GENERATE project to raise awareness of the importance of otolaryngologic research and to partner with patients and professionals to prioritize future research. This project determines what questions people want answered through surveys, focus groups, and interviews. The information collected is used to prioritize, develop, and find funding for the top projects based on popular interest. In addition, the Cochrane Ear, Nose and Throat (ENT) Disorders Group6 has partnered with the James Lind Alliance7 to identify and prioritize the top 10 uncertainties about the effects of treatments that they agree are most important. This effort brings together patients and clinicians to drive research agenIMPORTANCE Burden of disease should inform research prioritization.