Antiviral Efficacy of Oseltamivir Against Avian Influenza Virus in Avian Species

Important Findings For valuable bird species in zoos, novel eradication strategies for avian influenza virus (AIV) infection are needed, including antiviral treatments. The present study evaluated the anti-influenza efficacy of the potent neuraminidase inhibitor oseltamivir in avian species using the orders Galliformes (chickens) and Anseriformes (ducks). Viral replication of low pathogenic AIV was significantly reduced in the chicken model and completely reduced in the duck model.