of Pharmaceutical , Biological and Chemical Sciences Dry Powder Inhaler a Review

Present review is about Dry Powder Inhaler (DPI). Interest in DPIs as an effective, efficient and environmentally friendly way of delivering drugs to the lung has accelerated in recent years. Dry powder inhaler can meet these goals only with a suitable powder formulation, an efficient metering system, and a carefully selected device. When a DPI is actuated; the formulation is fluidized and enters the patient’s airways. Under the influence of inspiratory airflow, the drug particles separate from the carrier particles and are carried deep into the lungs, while the larger carrier particles impact on the oropharyngeal surfaces and are cleared. Successful delivery of dry powder aerosols to the lung requires careful consideration of the powder production process, formulation and inhaler device.