Impact of microRNA-145 to prevent vein graft disease in rabbit by regulation of smooth muscle cell phenotype Authors

Motoaki Ohnaka,Akira Marui,Kenichi Yamahara,Kenji Minakata,Kazuhiro Yamazaki,Motoyuki Kumagai,Hidetoshi Masumoto, Shiro Tanaka,Tadashi Ikeda,Ryuzo Sakata

semanticscholar（2017）

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摘要

Objective Since microRNA-145 (miR-145) is a specific mediator in the regulation of the proliferation and differentiation of smooth muscle cells (SMCs), we investigated the impact of miR-145 on intimal hyperplasia in the rabbit model of vein graft disease using electroporation-mediated gene transfer.

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